Robustness as an evolutionary principle

被引：83

作者：

Bornholdt, S

Sneppen, K

机构：

[1] Univ Kiel, Inst Theoret Phys, D-24098 Kiel, Germany

[2] Nord Inst Theoret Phys, DK-2100 Copenhagen, Denmark

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2000年 / 267卷 / 1459期

关键词：

evolution; gene regulation; epistasis; simulation; networks;

D O I：

10.1098/rspb.2000.1280

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We suggest simulating evolution of complex organisms using a model constrained solely hv the requirement of robustness in its expression patterns. This scenario is illustrated by evolving discrete logical networks with epigenetic properties. Evidence for dynamical features in the evolved networks is found that carl be related to biological observables.

引用

收藏

页码：2281 / 2286

页数：6

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