Autonomy in endemic goiter

被引：31

作者：

Corvilain, B

Van Sande, J

Dumont, JE

Bourdoux, P

Ermans, AM

机构：

[1] Free Univ Brussels, Erasme Hosp, Sch Med, Inst Interdisciplinary Res, B-1050 Brussels, Belgium

[2] Free Univ Brussels, Erasme Hosp, Dept Endocrinol, B-1050 Brussels, Belgium

[3] Brugman Hosp, Pediat Lab, Brussels, Belgium

[4] Univ Brussels, Sint Peter Hosp, Radioisotopes Dept, Brussels, Belgium

来源：

THYROID | 1998年 / 8卷 / 01期

关键词：

D O I：

10.1089/thy.1998.8.107

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The occurrence of hyperthyroidism in many individuals after introduction of iodine prophylaxis in endemic goiter areas can have dramatic consequences for the affected individuals. It indicates that in such individuals the increase of serum thyroid hormone level in response to iodine supplementation does not exert its normal negative feedback on thyroid activity, ie, that in such individuals some thyroid tissue has become autonomous. In this short review we summarize what is known about the possible mechanisms, cause, diagnosis, and consequences of thyroid autonomy.

引用

页码：107 / 113

页数：7

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