Anticholinesterase activities of cold and hot aqueous extracts of F. racemosa stem bark

被引：11

作者：

Ahmed, Faiyaz ^{[1
]}

Urooj, Asna ^{[1
]}

机构：

[1] Univ Mysore, Dept Studies Food Sci & Nutr, Mysore 570006, Karnataka, India

来源：

PHARMACOGNOSY MAGAZINE | 2010年 / 6卷 / 22期

关键词：

Acetylcholinesterase; Ayurveda; Alzhiemers; Ficus racemosa; medhya rasayana; ALZHEIMERS-DISEASE; FICUS-RACEMOSA; ACETYLCHOLINESTERASE; BRAHMI;

D O I：

10.4103/0973-1296.62897

中图分类号：

R914 [药物化学];

学科分类号：

100705 [微生物与生化药学];

摘要：

The present study evaluated the anticholinesterase activity of cold and hot aqueous extracts of Ficus racemosa stem bark against rat brain acetylcholinesterase in vitro. Both the cold aqueous extract (FRC) and the hot aqueous extract (FRH) exhibited a dose dependent inhibition of rat brain acetylcholinesterase. FRH showed significantly higher ( p <= 0.001) cholinesterase inhibitory activity compared to FRC; however, both the extracts did not show 50 inhibition of AChE at the doses tested (200-1000 g ml (-1) ). The IC 50 values of 1813 and 1331 g ml (-1) were deduced for FRC and FRH, respectively (calculated by extrapolation using Boltzmanns dose response analysis).

引用

页码：142 / 144

页数：3

共 19 条

[1]

Glucose-lowering, Hepatoprotective and Hypolipidemic Activities of Stem Bark of Ficus racemosa in Streptozotocin-Induced Diabetic Rats [J].