Enhanced Transmission of Antibiotic Resistance in Campylobacter jejuni Biofilms by Natural Transformation

被引：60

作者：

Bae, Junghee ^{[1
]}

Oh, Euna ^{[1
]}

Jeon, Byeonghwa ^{[1
]}

机构：

[1] Univ Alberta, Sch Publ Hlth, Edmonton, AB, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2014年 / 58卷 / 12期

基金：

加拿大自然科学与工程研究理事会;

关键词：

REVEALS;

D O I：

10.1128/AAC.04066-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Campylobacter jejuni is a leading food-borne pathogen, and its antibiotic resistance is of serious concern to public health worldwide. C. jejuni is naturally competent for DNA transformation and freely takes up foreign DNA harboring genetic information responsible for antibiotic resistance. In this study, we demonstrate that C. jejuni transfers antibiotic resistance genes more frequently in biofilms than in planktonic cells by natural transformation.

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收藏

页码：7573 / 7575

页数：3

相关论文

共 16 条

[1] Increased Emergence of Fluoroquinolone-Resistant Campylobacter jejuni in Biofilm [J].

Bae, Junghee ;

Jeon, Byeonghwa .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (10) :5195-5196

[2] Quinolone and macrolide resistance in Campylobacter jejuni and C-coli:: Resistance mechanisms and trends in human isolates [J].

Engberg, J ;

Aarestrup, FM ;

Taylor, DE ;

Gerner-Smidt, P ;

Nachamkin, I .

EMERGING INFECTIOUS DISEASES, 2001, 7 (01) :24-34

[3] Adverse health events associated with antimicrobial drug resistance in Campylobacter species:: A registry-based cohort study [J].

Helms, M ;

Simonsen, J ;

Olsen, KEP ;

Molbak, K .

JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (07) :1050-1055

[4] Transcriptional Regulation of the CmeABC Multidrug Efflux Pump and the KatA Catalase by CosR in Campylobacter jejuni [J].

Hwang, Sunyoung ;

Zhang, Qijing ;

Ryu, Sangryeol ;

Jeon, Byeonghwa .

JOURNAL OF BACTERIOLOGY, 2012, 194 (24) :6883-6891

[5] Role of Cj1211 in natural transformation and transfer of antibiotic resistance determinants in Campylobacter jejuni [J].

Jeon, Byeonghwa ;

Muraoka, Wayne ;

Sahin, Orhan ;

Zhang, Qijing .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (08) :2699-2708

[6]

Juhas M., 2013, CRIT REV MICROBIOL

[7] Proteomic analysis of Campylobacter jejuni 11168 biofilms reveals a role for the motility complex in biofilm formation [J].

Kalmokoff, Martin ;

Lanthier, Patricia ;

Tremblay, Tammy-Lynn ;

Foss, Mary ;

Lau, Peter C. ;

Sanders, Greg ;

Austin, John ;

Kelly, John ;

Szymanski, Christine M. .

JOURNAL OF BACTERIOLOGY, 2006, 188 (12) :4312-4320

[8] Development and application of an Insertional system for gene delivery and expression in Campylobacter jejuni [J].

Karlyshev, AV ;

Wren, BW .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (07) :4004-4013

[9] Campylobacter spp. distribution in biofilms on different surfaces in an agricultural watershed (Elk Creek, British Columbia): Using biofilms to monitor for Campylobacter [J].

Maal-Bared, Rasha ;

Bartlett, Karen H. ;

Bowie, William R. ;

Hall, Eric R. .

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2012, 215 (03) :270-278

[10] The sociobiology of biofilms [J].

Nadell, Carey D. ;

Xavier, Joao B. ;

Foster, Kevin R. .

FEMS MICROBIOLOGY REVIEWS, 2009, 33 (01) :206-224