Survivin structure: crystal unclear

被引：29

作者：

Shi, YG ^{[1
]}

机构：

[1] Princeton Univ, Lewis Thomas Lab, Dept Mol Biol, Princeton, NJ 08544 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2000年 / 7卷 / 08期

关键词：

D O I：

10.1038/77904

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three recent X-ray structures of the anti-apoptotic protein survivin reveal two different dimeric interfaces. More experiments are needed to determine the biologically relevant dimer interface and to probe survivin function on the basis of its structure.

引用

页码：620 / 623

页数：4

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