Changes in functional connectivity of human MT/V5 with visual motion input

被引:102
作者
Hampson, M
Olson, IR
Leung, HC
Skudlarski, P
Gore, JC
机构
[1] Yale Univ, Sch Med, Dept Diagnost Radiol, New Haven, CT 06510 USA
[2] Univ Penn, Ctr Cognit Neurosci, Philadelphia, PA 19104 USA
[3] SUNY Stony Brook, Dept Psychol, Stony Brook, NY 11794 USA
[4] Vanderbilt Univ, Inst Imaging Sci, Nashville, TN USA
关键词
fMRI; functional connectivity; low-frequency correlation; middle occipital gyrus; MT; neuroimaging; V5; visual motion;
D O I
10.1097/01.wnr.0000129997.95055.15
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
neural basis of human mental function is characterized by interactions between brain regions. Temporal correlations in MR signals between areas may provide one method for investigating these interactions. This approach was used to examine functional connectivity in the motion processing system of the human brain. Correlations between MT/V5 and other brain regions were examined in a resting state (without visual stimulation) and in an active state produced by viewing moving concentric circles. A network of regions consistent with the known functional anatomy of visual processing was correlated with MT/V5 during rest. When subjects were viewing motion, a more limited network was correlated with MT/V5, suggesting MT/V5 was acting in concert with a smaller network specific to the task.
引用
收藏
页码:1315 / 1319
页数:5
相关论文
共 25 条
[1]   DIRECTION AND ORIENTATION SELECTIVITY OF NEURONS IN VISUAL AREA MT OF THE MACAQUE [J].
ALBRIGHT, TD .
JOURNAL OF NEUROPHYSIOLOGY, 1984, 52 (06) :1106-1130
[2]   FUNCTIONAL CONNECTIVITY IN THE MOTOR CORTEX OF RESTING HUMAN BRAIN USING ECHO-PLANAR MRI [J].
BISWAL, B ;
YETKIN, FZ ;
HAUGHTON, VM ;
HYDE, JS .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :537-541
[3]   Hemifield visual motion stimulation: An example of interhemispheric crosstalk [J].
Brandt, T ;
Stephan, T ;
Bense, S ;
Yousry, TA ;
Dieterich, M .
NEUROREPORT, 2000, 11 (12) :2803-2809
[4]   The functional anatomy of attention to visual motion -: A functional MRI study [J].
Büchel, C ;
Josephs, O ;
Rees, G ;
Turner, R ;
Frith, CD ;
Friston, KJ .
BRAIN, 1998, 121 :1281-1294
[6]  
Cordes D, 2000, AM J NEURORADIOL, V21, P1636
[7]   MANY AREAS IN THE HUMAN BRAIN RESPOND TO VISUAL-MOTION [J].
DUPONT, P ;
ORBAN, GA ;
DEBRUYN, B ;
VERBRUGGEN, A ;
MORTELMANS, L .
JOURNAL OF NEUROPHYSIOLOGY, 1994, 72 (03) :1420-1424
[8]   Attentional modulation of effective connectivity from V2 to V5/MT in humans [J].
Friston, KJ ;
Büchel, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (13) :7591-7596
[9]   Detection of functional connectivity using temporal correlations in MR images [J].
Hampson, M ;
Peterson, BS ;
Skudlarski, P ;
Gatenby, JC ;
Gore, JC .
HUMAN BRAIN MAPPING, 2002, 15 (04) :247-262
[10]   Multiple sclerosis: Low-frequency temporal blood oxygen level-dependent fluctuations indicate reduced functional connectivity - Initial results [J].
Lowe, MJ ;
Phillips, MD ;
Lurito, JT ;
Mattson, D ;
Dzemidzic, M ;
Mathews, VP .
RADIOLOGY, 2002, 224 (01) :184-192