Cellular sources of tissue factor in endotoxemia and sepsis

被引：104

作者：

Pawlinski, Rafal ^{[1
]}

Mackman, Nigel ^{[1
]}

机构：

[1] Univ N Carolina, Div Hematol & Oncol, Dept Med, Chapel Hill, NC 27516 USA

来源：

THROMBOSIS RESEARCH | 2010年 / 125卷

基金：

美国国家卫生研究院;

关键词：

Tissue factor; Cell type; Sepsis; Endotoxemia; Disseminated intravascular coagulation; FACTOR PATHWAY INHIBITOR; FACTOR MESSENGER-RNA; FACTOR GENE-EXPRESSION; TUMOR-NECROSIS-FACTOR; EXTRINSIC PATHWAY; WHOLE-BLOOD; IN-VIVO; COAGULATION; ACTIVATION; THROMBOMODULIN;

D O I：

10.1016/j.thromres.2010.01.042

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sepsis is a systemic host response to infection by pathogenic microorganisms. Activation of the coagulation cascade during endotoxemia and sepsis leads to disseminated intravascular coagulation. This review focuses on tissue factor expression by hematopoietic and non-hematopoietic cells and its contribution to the activation of coagulation during endotoxemia and sepsis. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：S70 / S73

页数：4

共 53 条

[1] Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis -: A randomized controlled trial [J].

Abraham, E ;

Reinhart, K ;

Opal, S ;

Demeyer, I ;

Doig, C ;

Rodriguez, AL ;

Beale, R ;

Svoboda, P ;

Laterre, PF ;

Simon, S ;

Light, B ;

Spapen, H ;

Stone, J ;

Seibert, A ;

Peckelsen, C ;

De Deyne, C ;

Postier, R ;

Pettilä, V ;

Sprung, CL ;

Artigas, A ;

Percell, SR ;

Shu, V ;

Zwingelstein, C ;

Tobias, J ;

Poole, L ;

Stolzenbach, JC ;

Creasey, AA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (02) :238-247

[2] RECOMBINANT TUMOR-NECROSIS-FACTOR INDUCES PROCOAGULANT ACTIVITY IN CULTURED HUMAN VASCULAR ENDOTHELIUM - CHARACTERIZATION AND COMPARISON WITH THE ACTIONS OF INTERLEUKIN-1 [J].

BEVILACQUA, MP ;

POBER, JS ;

MAJEAU, GR ;

FIERS, W ;

COTRAN, RS ;

GIMBRONE, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (12) :4533-4537

[3] TISSUE FACTOR MESSENGER-RNA IN THP-1 MONOCYTIC CELLS IS REGULATED AT BOTH TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL LEVELS IN RESPONSE TO LIPOPOLYSACCHARIDE [J].

BRAND, K ;

FOWLER, BJ ;

EDGINGTON, TS ;

MACKMAN, N .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (09) :4732-4738

[4] Tissue factor activity in whole blood [J].

Butenas, S ;

Bouchard, BA ;

Brummel-Ziedins, KE ;

Parhami-Seren, B ;

Mann, KG .

BLOOD, 2005, 105 (07) :2764-2770

[5] Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs [J].

Camera, M ;

Frigerio, M ;

Toschi, V ;

Brambilla, M ;

Rossi, F ;

Cottell, DC ;

Maderna, P ;

Parolari, A ;

Bonzi, R ;

De Vincenti, O ;

Tremoli, E .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (09) :1690-1696

[6] Delayed treatment with recombinant human tissue factor pathway inhibitor improves survival in rabbits with gram-negative peritonitis [J].

Camerota, AJ ;

Creasey, AA ;

Patla, V ;

Larkin, AA ;

Fink, MP .

JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (03) :668-676

[7] Blockade of tissue factor - Treatment for organ injury in established sepsis [J].

Carraway, MS ;

Welty-Wolf, KE ;

Miller, DL ;

Ortel, TL ;

Idell, S ;

Ghio, AJ ;

Petersen, LC ;

Piantadosi, CA .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (09) :1200-1209

[8] CULTURED HUMAN-ENDOTHELIAL CELLS GENERATE TISSUE FACTOR IN RESPONSE TO ENDOTOXIN [J].

COLUCCI, M ;

BALCONI, G ;

LORENZET, R ;

PIETRA, A ;

LOCATI, D ;

DONATI, MB ;

SEMERARO, N .

JOURNAL OF CLINICAL INVESTIGATION, 1983, 71 (06) :1893-1896

[9] TISSUE FACTOR PATHWAY INHIBITOR REDUCES MORTALITY FROM ESCHERICHIA-COLI SEPTIC SHOCK [J].

CREASEY, AA ;

CHANG, ACK ;

FEIGEN, L ;

WUN, TC ;

TAYLOR, FB ;

HINSHAW, LB .

JOURNAL OF CLINICAL INVESTIGATION, 1993, 91 (06) :2850-2860

[10]

Dackiw APB, 1996, ARCH SURG-CHICAGO, V131, P1273

← 1 2 3 4 5 6 →