Neutral coordinate-organocatalysts in organic synthesis: Allylation of acylhydrazones with allyltrichlorosilanes

N,N-Dimethylformamide (DMF), sulfoxides, and phosphine oxides, etc., which are neutral, uncharged molecules and coordinate to silicon atoms of organosilicon reagents to activate nucleophilic addition, are defined as neutral coordinate-organocatalysts (NCOs). In the presence of NCOs, allylation reactions of acylhydrazones, useful imine surrogates, using allyltrichlorosilanes proceed smoothly to afford the synthetically useful racemic and non-racemic homoallylic amine derivatives in high yields with high diastereoselectivities.