Ion formation in MALDI:: The cluster ionization mechanism

被引：456

作者：

Karas, M ^{[1
]}

Krüger, R ^{[1
]}

机构：

[1] Univ Frankfurt, Inst Pharmaceut Chem, Bioctr, D-60439 Frankfurt, Germany

来源：

CHEMICAL REVIEWS | 2003年 / 103卷 / 02期

关键词：

D O I：

10.1021/cr010376a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The phenomena of cluster ionization mechanism in matrix-assisted laser desorption ionization (MALDI) was studied. The most of the bioanalytical applications dealt with analytes which contained charged functional groups. The results showed that the analytes with low ionization potential which promoted proton-transfer reactions, a direct photoionization or a charge transfer from matrix to analyte was feasible.

引用

页码：427 / 439

页数：13

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