Clinical application of immunosuppressive agents in renal transplantation

被引：14

作者：

First, MR

机构：

[1] Univ Cincinnati, Med Ctr, Dept Internal Med, Div Nephrol & Hypertens, Cincinnati, OH 45267 USA

[2] Univ Cincinnati, Med Ctr, Sect Transplantat, Cincinnati, OH 45267 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 1998年 / 78卷 / 01期

关键词：

D O I：

10.1016/S0039-6109(05)70635-6

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The availability of a number of new immunosuppressive drugs has resulted in significant improvements in the outcome of kidney transplantation. Currently 1-year graft survival rate for cadaver kidney transplants is approximately 85%. A number of new agents are presently in clinical studies. This article reviews the currently available agents and examines various aspects of induction and maintenance immunosuppressive therapy and the treatment of acute rejection episodes. Zn addition, the agents currently in clinical trials and future directions in immunosuppressive therapy are discussed.

引用

页码：61 / +

页数：17

共 32 条

[1]

ANDERSON P, 1993, CLIN TRANSPLANT, V7, P582

[2] EARLY VERSUS LATE ACUTE RENAL-ALLOGRAFT REJECTION - IMPACT ON CHRONIC REJECTION [J].

BASADONNA, GP ;

MATAS, AJ ;

GILLINGHAM, KJ ;

PAYNE, WD ;

DUNN, DL ;

SUTHERLAND, DER ;

GORES, PF ;

GRUESSNER, RWG ;

NAJARIAN, JS .

TRANSPLANTATION, 1993, 55 (05) :993-995

[3]

CECKA JM, 1990, CLIN TRANSPLANT 198, P425

[4]

Danovitch G, 1996, TRANSPLANTATION, V61, P722

[5]

DAWIDSON I, 1989, TRANSPLANTATION, V48, P575

[6] Efficacy and safety of tacrolimus versus cyclosporine in kidney and pancreas transplant recipients [J].

ElGhoroury, M ;

Hariharan, S ;

Peddi, VR ;

Munda, R ;

Schroeder, TJ ;

Demmy, AM ;

Alexander, JW ;

First, MR .

TRANSPLANTATION PROCEEDINGS, 1997, 29 (1-2) :649-651

[7]

FERGUSON RM, 1988, CLIN TRANSPLANT, V2, P285

[8]

FILO RS, 1980, TRANSPLANTATION, V30, P444

[9]

First MR, 1997, AM J KIDNEY DIS, V29, P303

[10]

GOLDSTEIN G, 1985, NEW ENGL J MED, V313, P337

← 1 2 3 4 →