CD154 (CD40 ligand)-deficient mice exhibit prolonged bleeding time and decreased shear-induced platelet aggregates

被引:30
作者
Crow, AR
Leytin, V
Starkey, AF
Rand, ML
Lazarus, AH
机构
[1] St Michaels Hosp, Toronto, ON M5B 1W8, Canada
[2] Canadian Blood Serv, Toronto, ON, Canada
[3] Hosp Sick Children, Toronto, ON M5G 1X8, Canada
关键词
D O I
10.1046/j.1538-7836.2003.t01-1-00115.x
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
引用
收藏
页码:850 / 852
页数:3
相关论文
共 16 条
[1]
CD40L stabilizes arterial thrombi by a β3 integrin-dependent mechanism [J].
André, P ;
Prasad, KSS ;
Denis, CV ;
He, M ;
Papalia, JM ;
Hynes, RO ;
Phillips, DR ;
Wagner, DD .
NATURE MEDICINE, 2002, 8 (03) :247-252
[2]
PLATELET ACTIVATION [J].
BLOCKMANS, D ;
DECKMYN, H ;
VERMYLEN, J .
BLOOD REVIEWS, 1995, 9 (03) :143-156
[3]
Crow AR, 2000, BLOOD, V96, p622A
[4]
A SOLUBLE FORM OF TRAP (CD40 LIGAND) IS RAPIDLY RELEASED AFTER T-CELL ACTIVATION [J].
GRAF, D ;
MULLER, S ;
KORTHAUER, U ;
VANKOOTEN, C ;
WEISE, C ;
KROCZEK, RA .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (06) :1749-1754
[5]
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells [J].
Henn, V ;
Slupsky, JR ;
Gräfe, M ;
Anagnostopoulos, I ;
Förster, R ;
Müller-Berghaus, G ;
Kroczek, RA .
NATURE, 1998, 391 (6667) :591-594
[6]
KONSTANTOPOULOS K, 1995, BIORHEOLOGY, V32, P73
[7]
Integrin cytoplasmic tyrosine motif is required for outside-in αIIbβ3 signalling and platelet function [J].
Law, DA ;
DeGuzman, FR ;
Heiser, P ;
Ministri-Madrid, K ;
Killeen, N ;
Phillips, DR .
NATURE, 1999, 401 (6755) :808-811
[8]
Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: Theoretical consideration and evaluation in thrombin-treated platelet populations [J].
Leytin, V ;
Mody, M ;
Semple, JW ;
Garvey, B ;
Freedman, J .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 269 (01) :85-90
[9]
Flow cytometry: A clinical test of platelet function [J].
Michelson, AD .
BLOOD, 1996, 87 (12) :4925-4936
[10]
CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression [J].
Miller, DL ;
Yaron, R ;
Yellin, MJ .
JOURNAL OF LEUKOCYTE BIOLOGY, 1998, 63 (03) :373-379