Determination of cyclamate radical by single-column ion-chromatography with a bulk acoustic wave detector

A chromatographic method based on a combination of single-column ion-chromatography separation with a bulk-acoustic-wave double-cell quartz crystal (DCQC) detector quantification for the determination of cyclamate in foodstuffs and body fluids was developed. The chromatographic system involves the use of a Shimadzu IC-A1 column with 5mM o-phthalic acid/methanol (90:10 V/V) as a mobile phase. The method exhibits an accept able detection limit and anti-interference ability. The DCQC detector has a low temperature coefficient and high conductance sensitivity. Foodstuff and body fluid sample such as ice cream, beverage, dried fruit of Areca catechu L., and urine were analysed successfully.