Involvement of the bed nucleus of the stria terminalis in the negative affective component of visceral and somatic pain in rats

被引:49
作者
Deyama, Satoshi
Nakagawa, Takayuki
Kaneko, Shuji
Uehara, Takashi
Minami, Masabumi [1 ]
机构
[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Dept Pharmacol, Sapporo, Hokkaido 0600812, Japan
[2] Kyoto Univ, Grad Sch Pharmaceut Sci, Dept Mol Pharmacol, Kyoto 6068501, Japan
关键词
aversion; bed nucleus of the stria terminalis (BST); emotion; extended amygdala; nociceptive behavior; pain;
D O I
10.1016/j.bbr.2006.10.021
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Using a conditioned place paradigm. we examined the involvement of the bed nucleus of the stria terminalis (BST) in the negative affective component of visceral and somatic pain induced by intraperitoneal acetic acid and intraplantar formalin injections, respectively, in rats. Bilateral BST lesions suppressed both the acetic acid- and formal in-induced conditioned place aversion, suggesting the crucial role of the BST in the negative affective component of visceral and somatic pain. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:367 / 371
页数:5
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