X-ray crystal structure and antioxidant activity of salidroside, a phenylethanoid glycoside

被引：46

作者：

Yu, Peizhong

Hu, Changqi ^{[1
]}

Meehan, Edward J.

Chen, Liqing

机构：

[1] Fudan Univ, Sch Pharm, Dept Chem Nat Drugs, Shanghai 200032, Peoples R China

[2] Univ Alabama, Grad Program Biotechnol, Dept Chem, Lab Struct Biol, Huntsville, AL 35899 USA

[3] Univ Alabama, Grad Program Chem & Mat Sci, Dept Chem, Lab Struct Biol, Huntsville, AL 35899 USA

来源：

CHEMISTRY & BIODIVERSITY | 2007年 / 4卷 / 03期

关键词：

D O I：

10.1002/cbdv.200790043

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The X-ray single-crystal structure of natural salidroside (= 2-(4-hydroxyphenyl)ethyl beta-D-glucopyranoside; 1), isolated from Cistanche deserticola, is reported for the first time, as well as its absolute configuration. The radical-scavenging activity of 1 towards the superoxide radical anion (O-2(.-)) was determined experimentally by chemiluminescence measurements of the pyrogallol-luminol system, and compared to that of the corresponding aglycone, i.e., tyrosol (= 4-(2-hydroxyethyl)phenol; 2).

引用

页码：508 / 513

页数：6

共 20 条

[1]

*BRUK AXS INC, 1999, SMART VERS 5 049

[2]

*BRUK AXS INC, 1999, SAINT VERS 5 00

[3] ON ENANTIOMORPH-POLARITY ESTIMATION [J].