Electronically promoted payne rearrangement of 3-CF3-2,3-epoxyalcohols

被引：21

作者：

Yamazaki, T ^{[1
]}

Ichige, T ^{[1
]}

Kitazume, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Bioengn, Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 22期

关键词：

D O I：

10.1021/ol048229x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Smooth and selective Payne rearrangement was achieved for the above types of epoxyalcohols with a CF3 group so as to form thermodynamically more stable alkoxides, where the strongly electron-withdrawing nature of this moiety played a significantly important role and was proved to overcome increased steric instability of epoxides from syn-E to anti-Z isomers.

引用

收藏

页码：4073 / 4076

页数：4

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