The Ashbya Genome Database (AGD) - a tool for the yeast community and genome biologists

被引:14
作者
Hermida, L
Brachat, S
Voegeli, S
Philippsen, P
Primig, M
机构
[1] Biozentrum, Dept Appl Microbiol, CH-4056 Basel, Switzerland
[2] Swiss Inst Bioinformat, CH-4056 Basel, Switzerland
关键词
D O I
10.1093/nar/gki009
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Ashbya Genome Database (AGD) is a comprehensive online source of information covering genes from the filamentous fungus Ashbya gossypii. The database content is based upon comparative genome annotation between A.gossypii and the closely related budding yeast Saccharomyces cerevisiae taking both sequence similarity and synteny (conserved order and orientation) into account. Release 2 of AGD contains 4718 protein-encoding loci located across seven chromosomes. Information can be retrieved using systematic or standard locus names from A.gossypii as well as budding and fission yeast. Approximately 90% of the genes in the genome of A.gossypii are homologous and syntenic to loci of budding yeast. Therefore, AGD is a useful tool not only for the various yeast communities in general but also for biologists who are interested in evolutionary aspects of genome research and comparative genome annotation. The database provides scientists with a convenient graphical user interface that includes various locus search and genome browsing options, data download and export functionalities and numerous reciprocal links to external databases including SGD, MIPS, GeneDB, KEGG, Germ-Online and Swiss-Prot/TrEMBL. AGD is accessible at http://agd.unibas.ch/.
引用
收藏
页码:D348 / D352
页数:5
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