The force be with you: ATP in gut mechanosensory transduction

被引：60

作者：

Cooke, HJ ^{[1
]}

Wunderlich, J

Christofi, FL

机构：

[1] Ohio State Univ, Dept Neurosci, Columbus, OH 43210 USA

[2] Ohio State Univ, Dept Anesthesiol, Columbus, OH 43210 USA

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2003年 / 18卷

关键词：

D O I：

10.1152/nips.01411.2002

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Nucleotides such as ATP and UTP are everywhere. They play a key role in transducing mechanosensory signals via P2Y receptors in the large intestine or colon, leading to secretion of the sensory mediator 5-HT, and act as autocrine, paracrine, or neurocrine mediators in neural reflexes regulating chloride secretion.

引用

页码：43 / 49

页数：7

共 20 条

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