Apoptosis - Phagocytic docking without shocking

被引：198

作者：

Savill, J ^{[1
]}

机构：

[1] Univ Nottingham Hosp, Div Renal & Inflammatory Dis, Nottingham NG7 2UH, England

来源：

NATURE | 1998年 / 392卷 / 6675期

关键词：

D O I：

10.1038/33025

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Apoptosis, or programmed cell death, has been a vibrant research topic for some time. But there has been little study of the process by which dying cells are cleared away — that is, how they are recognized, engulfed and degraded by phagocytes. Two studies (one involving the nematodeCaenorhabditis elegans, the other human cells) now implicate the CED-5 molecule in the cytoskeletal reorganization necessary for the engulfing cell to do its job, and the CD14 protein in the process of tethering apoptotic cells to phagocytes.

引用

页码：442 / 443

页数：2

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