AMPA receptor trafficking and long-term potentiation

被引:181
作者
Malinow, R [1 ]
机构
[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
excitatory; transmission; memory; long-term potentiation; experience-dependent plasticity;
D O I
10.1098/rstb.2002.1233
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Activity-dependent changes in synaptic function are believed to underlie the formation of memories. A prominent example is long-term potentiation (LTP), whose mechanisms have been the subject of considerable scrutiny over the past few decades. I review studies from our laboratory that support a critical role for AMPA receptor trafficking in LTP and experience-dependent plasticity.
引用
收藏
页码:707 / 714
页数:8
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