Cerebral manifestation of Erdheim-Chester disease: Clinical and radiologic findings

被引：45

作者：

Bohlega, S

Alwatban, J

Tulbah, A

Bakheet, SM

Powe, J

机构：

[1] King Faisal Specialist Hosp & Res Ctr, Dept Neurosci, Neurol Sect, Riyadh 11211, Saudi Arabia

[2] King Faisal Specialist Hosp & Res Ctr, Dept Radiol, Sect Med Imaging, Riyadh 11211, Saudi Arabia

[3] King Faisal Specialist Hosp & Res Ctr, Dept Pathol & Lab Med, Riyadh 11211, Saudi Arabia

来源：

NEUROLOGY | 1997年 / 49卷 / 06期

关键词：

D O I：

10.1212/WNL.49.6.1702

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 33-year-old woman presented with a 3-year history of progressive numbness in the hand, cerebellar ataxia, limb weakness, nystagmus, and dysarthria. T2-weighted MRI revealed abnormal foci of increased signal intensity mimicking demyelinating plaques in the periventricular white matter, and brain (18)FDG-PET scan showed increased uptake in the pens. Biopsy from a tibial lesion showed aggregates of foamy histiocytes in the intertrabecular spaces replacing the bone marrow, characteristic of Erdheim-Chester disease. The patient was treated with craniospinal radiation. After 6 months, the clinical picture was stable and the MRI was unchanged.

引用

页码：1702 / 1705

页数：4

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