MeOPEG-bounded azide cycloadditions to alkynyl dipolarophiles

被引：47

作者：

Garanti, L ^{[1
]}

Molteni, G ^{[1
]}

机构：

[1] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(02)02844-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The MeOPEG-supported azide 2 was reacted in the presence of a number of alkynyl dipolarophiles. The corresponding 1-MeOPEG-supported-1,2,3-triazoles were obtained in nearly quantitative yields. Acidic hydrolysis of the cycloadducts 5b and 6b caused the removal of the MeOPEG pendant giving 4-methoxycarbonyl-1,2,3-triazole 9 and 5-methoxycarbonyl-1,2,3-triazole 10, respectively. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1133 / 1135

页数：3

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