Fibrogenic signalling in hepatic stellate cells

被引:88
作者
Mann, Derek A. [1 ]
Marra, Fabio [2 ]
机构
[1] Newcastle Univ, Liver Res Grp, Inst Cellular Med, Sch Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[2] Univ Florence, Dipartimento Med Interna, I-50134 Florence, Italy
关键词
Hepatic stellate cells; Transcription; Receptors; Cytokines; Signaling; CHRONIC LIVER-DISEASES; FIBROSIS; TARGETS; RECEPTORS;
D O I
10.1016/j.jhep.2010.02.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:949 / 950
页数:2
相关论文
共 10 条
[1]
Liver fibrosis [J].
Bataller, R ;
Brenner, DA .
JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (02) :209-218
[2]
Bertolani Cristiana, 2008, Pathophysiology, V15, P91, DOI 10.1016/j.pathophys.2008.05.001
[3]
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis [J].
Elsharkawy, AM ;
Oakley, F ;
Mann, DA .
APOPTOSIS, 2005, 10 (05) :927-939
[4]
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver [J].
Friedman, Scott L. .
PHYSIOLOGICAL REVIEWS, 2008, 88 (01) :125-172
[5]
Gao B, 2009, J LEUKOCYTE BIOL, V86, P513, DOI [10.1189/jlb.0309135, 10.1189/JLB.0309135]
[6]
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets [J].
Gressner, A. M. ;
Weiskirchen, R. .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2006, 10 (01) :76-99
[7]
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ [J].
Iredale, John P. .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (03) :539-548
[8]
Cannabinoid receptors as new targets of antifibrosing strategies during chronic liver diseases [J].
Mallat, Ariane ;
Teixeira-Clerc, Fatima ;
Deveaux, Vanessa ;
Lotersztajn, Sophie .
EXPERT OPINION ON THERAPEUTIC TARGETS, 2007, 11 (03) :403-409
[9]
Transcriptional regulation of hepatic stellate cells [J].
Mann, Jelena ;
Mann, Derek A. .
ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (7-8) :497-512
[10]
Toll-like receptors as targets in chronic liver diseases [J].
Mencin, A. ;
Kluwe, J. ;
Schwabe, R. F. .
GUT, 2009, 58 (05) :704-720