New measurements of DNA twist elasticity

被引：21

作者：

Nelson, P ^{[1
]}

机构：

[1] Univ Penn, Dept Phys & Astron, Philadelphia, PA 19104 USA

来源：

BIOPHYSICAL JOURNAL | 1998年 / 74卷 / 05期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0006-3495(98)77958-5

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally constrained single molecules give the first direct measurement of this new material parameter. We extract its value from a recent experiment, Finally, we sketch the effect of constrained twist on entropic elasticity of DNA arising from the connection between Link, Twist, and Writhe.

引用

页码：2501 / 2503

页数：3

共 16 条

[1] ENTROPIC ELASTICITY OF LAMBDA-PHAGE DNA [J].

BUSTAMANTE, C ;

MARKO, JF ;

SIGGIA, ED ;

SMITH, S .

SCIENCE, 1994, 265 (5178) :1599-1600

[2] DNA: An extensible molecule [J].

Cluzel, P ;

Lebrun, A ;

Heller, C ;

Lavery, R ;

Viovy, JL ;

Chatenay, D ;

Caron, F .

SCIENCE, 1996, 271 (5250) :792-794

[3]

FULLER FB, 1978, P NATL ACAD SCI USA, V75, P3357

[4] Direct determination of DNA twist-stretch coupling [J].

Kamien, RD ;

Lubensky, TC ;

Nelson, P ;

OHern, CS .

EUROPHYSICS LETTERS, 1997, 38 (03) :237-242

[5] Stretching must twist DNA [J].

Marko, JF .

EUROPHYSICS LETTERS, 1997, 38 (03) :183-188

[6] Stretching DNA [J].

Marko, JF ;

Siggia, ED .

MACROMOLECULES, 1995, 28 (26) :8759-8770

[7] Elasticity theory of a twisted stack of plates [J].

O'Hern, CS ;

Kamien, RD ;

Lubensky, TC ;

Nelson, P .

EUROPEAN PHYSICAL JOURNAL B, 1998, 1 (01) :95-102

[8]

Saenger W, 1984, Principles of Nucleic Acid Structure

[9] Overstretching B-DNA: The elastic response of individual double-stranded and single-stranded DNA molecules [J].

Smith, SB ;

Cui, YJ ;

Bustamante, C .

SCIENCE, 1996, 271 (5250) :795-799

[10] DIRECT MECHANICAL MEASUREMENTS OF THE ELASTICITY OF SINGLE DNA-MOLECULES BY USING MAGNETIC BEADS [J].

SMITH, SB ;

FINZI, L ;

BUSTAMANTE, C .

SCIENCE, 1992, 258 (5085) :1122-1126

← 1 2 →