Are antiplatelet effects of clopidogrel inhibited by atorvastatin? A research question formulated but not yet adequately tested

被引:31
作者
Serebruany, VL
Steinhubl, SR
Hennekens, CH
机构
[1] Sinai Thrombosis Ctr, Baltimore, MD USA
[2] Univ N Carolina, Chapel Hill, NC USA
[3] Univ Miami, Miami, FL 33152 USA
关键词
editorials; platelets; statins; drugs;
D O I
10.1161/01.CIR.0000065125.50640.70
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1568 / 1569
页数:2
相关论文
共 13 条
[1]  
Baigent C, 2002, BMJ-BRIT MED J, V324, P71, DOI 10.1136/bmj.324.7329.71
[2]   The new national cholesterol education program guidelines [J].
Eidelman, RS ;
Lamas, GA ;
Hennekens, CH .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (18) :2033-2036
[3]   A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) [J].
Gent, M ;
Beaumont, D ;
Blanchard, J ;
Bousser, MG ;
Coffman, J ;
Easton, JD ;
Hampton, JR ;
Harker, LA ;
Janzon, L ;
Kusmierek, JJE ;
Panak, E ;
Roberts, RS ;
Shannon, JS ;
Sicurella, J ;
Tognoni, G ;
Topol, EJ ;
Verstraete, M ;
Warlow, C .
LANCET, 1996, 348 (9038) :1329-1339
[4]   Cholesterol lowering with statin drugs: Evidence in women - Reply [J].
Hebert, P ;
Chan, KS ;
Gaziano, JM ;
Hennekens, CH .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (20) :1660-1661
[5]   Increasing burden of cardiovascular disease - Current knowledge and future directions for research on risk factors [J].
Hennekens, CH .
CIRCULATION, 1998, 97 (11) :1095-1102
[6]   Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins) [J].
Igel, M ;
Sudhop, T ;
vonBergmann, K .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2001, 57 (05) :357-364
[7]   Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation - A new drug-drug interaction [J].
Lau, WC ;
Waskell, LA ;
Watkins, PB ;
Neer, CJ ;
Horowitz, K ;
Hopp, AS ;
Tait, AR ;
Carville, DGM ;
Guyer, KE ;
Bates, ER .
CIRCULATION, 2003, 107 (01) :32-37
[8]   Structure and stereochemistry of the active metabolite of clopidogrel [J].
Pereillo, JM ;
Maftouh, M ;
Andrieu, A ;
Uzabiaga, MF ;
Fedeli, O ;
Savi, P ;
Pascal, M ;
Herbert, JM ;
Maffrand, JP ;
Picard, C .
DRUG METABOLISM AND DISPOSITION, 2002, 30 (11) :1288-1295
[9]   Identification and biological activity of the active metabolite of clopidogrel [J].
Savi, P ;
Pereillo, JM ;
Uzabiaga, MF ;
Combalbert, J ;
Picard, C ;
Maffrand, JP ;
Pascal, M ;
Herbert, JM .
THROMBOSIS AND HAEMOSTASIS, 2000, 84 (05) :891-896
[10]  
SEREBRUANY VL, 2001, ATHEROSCLEROSIS, V239, P259