Synthesis and Characterization of Gold@Gold(I) - Thiomalate Core@Shell Nanoparticles

被引：52

作者：

Corthey, Gaston ^{[1
]}

Giovanetti, Lisandro J. ^{[1
]}

Ramallo-Lopez, Jose M. ^{[1
]}

Zelaya, Eugenia ^{[2
]}

Rubert, Aldo A. ^{[1
]}

Benitez, Guillermo A. ^{[1
]}

Requejo, Felix G. ^{[1
]}

Fonticelli, Mariano H. ^{[1
]}

Salvarezza, Roberto C. ^{[1
]}

机构：

[1] Univ Nacl La Plata, CONICET, INIFTA, RA-1900 La Plata, Argentina

[2] Consejo Nacl Invest Cient & Tecn, Ctr Atom Bariloche, Comis Nacl Energia Atom, RA-8400 San Carlos De Bariloche, Rio Negro, Argentina

来源：

ACS NANO | 2010年 / 4卷 / 06期

关键词：

gold nanoparticles; core@shell nanoparticles; thiomalic acid; mercaptosuccinic acid; gold(I) - thiomalate; rheumatoid arthritis; antiarthritic drugs; X-RAY-ABSORPTION; CAPPED GOLD NANOPARTICLES; SELF-ASSEMBLED MONOLAYERS; ANTIARTHRITIC DRUG; SIZE DISTRIBUTION; AU NANOPARTICLES; CLUSTERS; SPECTROSCOPY; STABILITY; COMPLEXES;

D O I：

10.1021/nn100272q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, the synthesis of gold@gold(I)- thiolate core@shell nanoparticles is described for the first time. The chemical nature and structure of these nanoparticles were characterized by a multi-technique approach. The prepared particles consist of gold metallic cores, about 1 nm in size, surrounded by stable gold(I)- thiomalate shells (Au@Au(I)-TM). These nanoparticles could be useful in medicine due to the interesting properties that gold(I)-thiomalate has against rheumatoid arthritis. Furthermore, the described results give new insights in the synthesis and characterization of metallic and core@shell nanoparticles.

引用

页码：3413 / 3421

页数：9

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