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Why do we age?

被引：1189
作者：
Kirkwood, TBL [1 ]
Austad, SN
机构：
[1] Newcastle Gen Hosp, Inst Hlth Elderly, Dept Gerontol, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
[2] Univ Idaho, Dept Biol Sci, Moscow, ID 83844 USA
来源：
NATURE | 2000年 / 408卷 / 6809期
关键词：
D O I：
10.1038/35041682
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The evolutionary theory of ageing explains why ageing occurs, giving valuable insight into the mechanisms underlying the complex cellular and molecular changes that contribute to senescence. Such understanding also helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.
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页码：233 / 238
页数：6
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