Molecular biology of varicella-zoster virus - A review prepared for the UK Advisory Group on Chickenpox

被引：12

作者：

Harper, DR ^{[1
]}

Gilbert, RL

Jeffries, DJ

机构：

[1] St Bartholomews Hosp, Dept Virol, London EC1A 7BE, England

[2] Royal London Hosp, Sch Med & Dent, London E1 1BB, England

来源：

JOURNAL OF INFECTION | 1998年 / 36卷

关键词：

D O I：

10.1016/S0163-4453(98)80149-7

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Varicella-zoster virus (human herpesvirus 3; VZV) is one of eight herpes viruses that routinely infect humans. It is classified as a member of the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae. Of the other human herpes viruses it is most closely related to the herpes simplex viruses (also members of the Alphaherpesvirinae). Like all herpes viruses, the virus has a large double-stranded DNA genome within an icosahedral nucleocapsid. This is surrounded by a proteinaceous tegument and a trilaminar membrane derived from host-cell membranes into which the viral glycoproteins are inserted. The structure of the virion is summarized in Fig. 1.

引用

页码：1 / 10

页数：10