Little Lambda, who made thee?

被引:39
作者
Gottesman, ME
Weisberg, RA
机构
[1] Columbia Univ, Inst Canc Res, New York, NY 10032 USA
[2] NIH, Mol Genet Lab, Bethesda, MD 20892 USA
关键词
D O I
10.1128/MMBR.68.4.796-813.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The study of the bacteriophage X has been critical to the discipline of molecular biology. It was the source of key discoveries in the mechanisms of, among other processes, gene regulation, recombination, and transcription initiation and termination. We trace here the events surrounding these findings and draw on the recollections of the participants. We show how a particular atmosphere of interactions among creative scientists yielded spectacular insights into how living things work.
引用
收藏
页码:796 / +
页数:19
相关论文
共 209 条
[1]  
Adhya S, 1974, Basic Life Sci, V3, P213
[2]   CONTROL OF TRANSCRIPTION TERMINATION [J].
ADHYA, S ;
GOTTESMAN, M .
ANNUAL REVIEW OF BIOCHEMISTRY, 1978, 47 :967-996
[3]   RELEASE OF POLARITY IN ESCHERICHIA-COLI BY GENE N OF PHAGE LAMBDA - TERMINATION AND ANTITERMINATION OF TRANSCRIPTION [J].
ADHYA, S ;
GOTTESMAN, M ;
DECROMBR.B .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (06) :2534-2538
[4]   HISTIDINE OPERON [J].
AMES, BN ;
HARTMAN, PE .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1963, 28 :349-&
[5]  
[Anonymous], DNA INSERTION ELEMEN
[6]  
APPLEYARD RK, 1953, QUANT BIOL, V18, P95
[7]   ON HOST-CONTROLLED MODIFICATION OF BACTERIOPHAGE LAMBDA [J].
ARBER, W ;
HATTMAN, S ;
DUSSOIX, D .
VIROLOGY, 1963, 21 (01) :30-+
[8]   HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA-COLI .1. HOST CONTROLLED MODIFICATION OF BACTERIOPHAGE LAMBDA [J].
ARBER, W ;
DUSSOIX, D .
JOURNAL OF MOLECULAR BIOLOGY, 1962, 5 (01) :18-+
[9]   DNA MODIFICATION AND RESTRICTION [J].
ARBER, W ;
LINN, S .
ANNUAL REVIEW OF BIOCHEMISTRY, 1969, 38 :467-+
[10]  
Arber W, 1974, Prog Nucleic Acid Res Mol Biol, V14, P1, DOI 10.1016/S0079-6603(08)60204-4