Rapid acquisition of stable azole resistance by Candida glabrata isolates obtained before the clinical introduction of Fluconazole

被引：83

作者：

Borst, A ^{[1
]}

Raimer, MT ^{[1
]}

Warnock, DW ^{[1
]}

Morrison, CJ ^{[1
]}

Arthington-Skaggs, BA ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Mycot Dis Branch, Div Bacterial & Mycot Dis, Natl Ctr Infect Dis, Atlanta, GA 30333 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 02期

关键词：

D O I：

10.1128/AAC.49.2.783-787.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Five azole-susceptible Candida glabrata isolates obtained before 1975 became resistant to fluconazole, itraconazole, and voriconazole within 4 days of in vitro fluconazole exposure. This cross-resistance was stable for at least 4 months after removal of fluconazole and was associated with increased CgCDR1 and CgCDR2 expression.

引用

页码：783 / 787

页数：5

共 28 条

[1] The epidemiology of hematogenous candidiasis caused by different Candida species [J].

AbiSaid, D ;

Anaissie, E ;

Uzun, O ;

Raad, I ;

Pinzcowski, H ;

Vartivarian, S .

CLINICAL INFECTIOUS DISEASES, 1997, 24 (06) :1122-1128

[2]

[Anonymous], 2002, M27A2 CLSI

[3] Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis [J].

Bennett, JE ;

Izumikawa, K ;

Marr, KA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (05) :1773-1777

[4] Reversible fluconazole resistance in Candida albicans: A potential in vitro model [J].

Calvet, HM ;

Yeaman, MR ;

Filler, SG .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (03) :535-539

[5] Evolution of drug resistance in experimental populations of Candida albicans [J].

Cowen, LE ;

Sanglard, D ;

Calabrese, D ;

Sirjusingh, C ;

Anderson, JB ;

Kohn, LM .

JOURNAL OF BACTERIOLOGY, 2000, 182 (06) :1515-1522

[6] In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata [J].

Defontaine, A ;

Bouchara, JP ;

Declerk, P ;

Planchenault, C ;

Chabasse, D ;

Hallet, JN .

JOURNAL OF MEDICAL MICROBIOLOGY, 1999, 48 (07) :663-670

[7] Epidemiology of candidemia: 3-year results from the emerging infections and the epidemiology of Iowa organisms study [J].

Diekema, DJ ;

Messer, SA ;

Brueggemann, AB ;

Coffman, SL ;

Doern, GV ;

Herwaldt, LA ;

Pfaller, MA .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (04) :1298-1302

[8] Rapid identification of Candida species with species-specific DNA probes [J].

Elie, CM ;

Lott, TJ ;

Reiss, E ;

Morrison, CJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (11) :3260-3265

[9] Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program [J].

Hajjeh, RA ;

Sofair, AN ;

Harrison, LH ;

Lyon, GM ;

Arthington-Skaggs, BA ;

Mirza, SA ;

Phelan, M ;

Morgan, J ;

Lee-Yang, W ;

Ciblak, MA ;

Benjamin, LE ;

Sanza, LT ;

Huie, S ;

Yeo, SF ;

Brandt, ME ;

Warnock, DW .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (04) :1519-1527

[10] Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors [J].

Henry, KW ;

Nickels, JT ;

Edlind, TD .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (10) :2693-2700

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