Avoiding the SCAMs

被引：3

作者：

Kidd, Thomas

Condron, Barry

机构：

[1] Univ Nevada, Dept Biol, Reno, NV 89557 USA

[2] Univ Virginia, Dept Biol, Charlottesville, VA 22903 USA

来源：

NEURON | 2007年 / 54卷 / 03期

关键词：

D O I：

10.1016/j.neuron.2007.04.018

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Dendrites from the same neuron usually avoid contact with one another, a behavior known as self-avoidance. In this issue of Neuron and in the upcoming May 4, 2007 issue of Cell, a pair of studies by Soba et al. and Hughes et al. and a study by Matthews et al., respectively, identify products from the highly alternatively spliced Dscam gene as central to this behavior in Drosophila. Signaling induced by adhesion between identical isoforms triggers repulsion between sister dendrites.

引用

收藏

页码：350 / 352

页数：3

相关论文

共 14 条

[1] Evolution of the neurotrophin signaling system in invertebrates [J].

Bothwell, Mark .

BRAIN BEHAVIOR AND EVOLUTION, 2006, 68 (03) :124-132

[2]

Canal I, 1998, J NEUROSCI, V18, P999

[3] Early development of ocular dominance columns [J].

Crowley, JC ;

Katz, LC .

SCIENCE, 2000, 290 (5495) :1321-1324

[4] Control of dendritic field formation in Drosophila:: The roles of flamingo and competition between homologous neurons [J].

Gao, FB ;

Kohwi, M ;

Brenman, JE ;

Jan, LY ;

Jan, YN .

NEURON, 2000, 28 (01) :91-101

[5] Neurotrophic and gliatrophic contexts in Drosophila [J].

Hidalgo, Alicia ;

Learte, Anabel R. ;

McQuilton, Peter ;

Pennack, Jenny ;

Zhu, Bangfu .

BRAIN BEHAVIOR AND EVOLUTION, 2006, 68 (03) :173-180

[6] Activity-independent prespecification of synaptic partners in the visual map of Drosophila [J].

Hiesinger, P. Robin ;

Zhai, R. Grace ;

Zhou, Yi ;

Koh, Tong-Wey ;

Mehta, Sunil Q. ;

Schulze, Karen L. ;

Cao, Yu ;

Verstreken, Patrik ;

Clandinin, Thomas R. ;

Fischbach, Karl-Friedrich ;

Meinertzhagen, Ian A. ;

Bellen, Hugo J. .

CURRENT BIOLOGY, 2006, 16 (18) :1835-1843

[7] Homophilic Dscam interactions control complex dendrite morphogenesis [J].

Hughes, Michael E. ;

Bortnick, Rachel ;

Tsubouchi, Asako ;

Baumer, Philipp ;

Kondo, Masahiro ;

Uemura, Tadashi ;

Schmucker, Dietmar .

NEURON, 2007, 54 (03) :417-427

[8] The control of dendrite development [J].

Jan, YN ;

Jan, LY .

NEURON, 2003, 40 (02) :229-242

[9] Phenotypes of Drosophila brain neurons in primary culture reveal a role for fascin in neurite shape and trajectory [J].

Kraft, Robert ;

Escobar, Mindy M. ;

Narro, Martha L. ;

Kurtis, Jackie L. ;

Efrat, Alon ;

Barnard, Kobus ;

Restifo, Linda L. .

JOURNAL OF NEUROSCIENCE, 2006, 26 (34) :8734-8747

[10]

MATTHEWS BJ, 2007, IN PRESS CELL, V129