Ankyrins

被引:107
作者
Rubtsov, AM [1 ]
Lopina, OD [1 ]
机构
[1] Moscow MV Lomonosov State Univ, Sch Biol, Dept Biochem, Moscow 199899, Russia
基金
俄罗斯基础研究基金会;
关键词
ankyrin; membrane cytoskeleton; ankyrin repeat; signal transduction; protein sorting;
D O I
10.1016/S0014-5793(00)01924-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review is focused on ankyrin which is a protein linker between the integral membrane proteins and spectrin-based cytoskeleton. Structure and distribution of different ankyrin isoforms that are products of alternative-spliced genes are described. Interaction of ankyrins with various membranes is considered. Special attention is paid to ankyrin participation in signal transduction and in assembly of integral membrane proteins in specialized membrane domains. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
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页码:1 / 5
页数:5
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