The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines

被引：30

作者：

Atlan, V ^{[1
]}

Bienaymé, H ^{[1
]}

El Kaim, L ^{[1
]}

Majee, A ^{[1
]}

机构：

[1] Ecole Natl Super Tech Avancees, Lab Chim & Proc, F-75015 Paris, France

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 17期

关键词：

D O I：

10.1039/b002750m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon-carbon bonds.

引用

页码：1585 / 1586

页数：2