Frondoside C, a new nonholostane triterpene glycoside from the sea cucumber Cucumaria frondosa:: structure and cytotoxicity of its desulfated derivative

被引：30

作者：

Avilov, SA ^{[1
]}

Drozdova, OA

Kalinin, VI

Kalinovsky, AI

Stonik, VA

Gudimova, EN

Riguera, R

Jiménez, C

机构：

[1] Russian Acad Sci, Far E Div, Pacific Inst Bioorgan Chem, Vladivostok 690022, Russia

[2] Russian Acad Sci, Kolsky Sci Ctr, Murmansk Marine Biol Inst, Dalniye Zelentsky 184631, Murmansk Dist, Russia

[3] Univ Santiago de Compostela, Fac Quim, Dept Quim Organ, Santiago De Compostela 15706, Spain

[4] Univ Santiago de Compostela, Inst Acuicultura, Santiago De Compostela 15706, Spain

[5] Univ A Coruna, Fac Ciencias, Dept Quim Fundamental & Ind, La Coruna 15071, Spain

来源：

CANADIAN JOURNAL OF CHEMISTRY | 1998年 / 76卷 / 02期

关键词：

Cucumaria frondosa; sea cucumbers; frondosides; triterepene glycosides; antitumor activity;

D O I：

10.1139/cjc-76-2-137

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Frondoside C (I) is a new sulfated nonholostane triterpene glycoside obtained (with the glycosides closed by aglycone structure as impurities) from the sea cucumber Cucumaria frondosa. Its structure has been elucidated on the basis of spectral data (NMR and MS) of compound I and of its desulfated derivative (2) obtained by solvolysis. Frondoside C (1) is just the seventh glycoside reported from sea cucumbers, having a lanostane-type aglycone devoid of the typical 18(20)-lactone ring.

引用

页码：137 / 141

页数：5

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