The role of chromosomal RNAs in marking the X for dosage compensation

被引：33

作者：

Kelley, RL

Kuroda, MI

机构：

[1] Baylor Coll Med, Houston, TX 77030 USA

[2] Howard Hughes Med Inst, Dept Mol & Cellular Biol, Houston, TX 77030 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2000年 / 10卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00127-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Both flies and mammals remodel the architecture of the X chromosome to achieve dosage compensation. A novel class of noncoding RNAs that paint entire chromosomes are centrally involved in this process. The genes encoding these unusual RNAs are themselves located on the X, and are key sites that target the X for dosage compensation.

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页码：555 / 561

页数：7

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