LiOH-Catalyzed Simple Ring Opening of Epoxides Under Solvent-Free Conditions

被引：18

作者：

Azizi, Najmedin ^{[1
]}

Khajeh-Amiri, Alireza ^{[1
]}

Ghafuri, Hossein ^{[1
]}

Bolourtchian, Mohammad ^{[1
]}

机构：

[1] Chem & Chem Engn Res Ctr Iran, Tehran, Iran

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2010年 / 185卷 / 07期

关键词：

Epoxide; -hydroxy nitriles; -hydroxy sulfide; lithium hydroxide; solvent free conditions; thiol; BETA-HYDROXY SULFOXIDES; ONE-POT SYNTHESIS; ACETONE CYANOHYDRIN; EFFICIENT CATALYST; MESO-EPOXIDES; THIOLYSIS; 1,2-EPOXIDES; ALCOHOLS; WATER; THIOPHENOL;

D O I：

10.1080/10426500903127573

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

LiOH has been found to be a very simple and selective catalyst for the rapid and mild synthesis of -hydroxy sulfides and -hydroxyl nitriles by ring opening of epoxides with aromatic, aliphatic, and heterocyclic thiols and trimethylsilyl cyanide at room temperature under solvent free conditions. All the reactions proceeded satisfactorily in short times and afforded the corresponding products in good to excellent yields with high regioselectivity and chemoselectivity under mild reaction conditions.

引用

页码：1550 / 1557

页数：8

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