Nanocharacterization in Dentistry

被引：33

作者：

Sharma, Shivani ^{[1
,2
]}

Cross, Sarah E. ^{[1
,2
]}

Hsueh, Carlin ^{[1
]}

Wali, Ruseen P. ^{[1
]}

Stieg, Adam Z. ^{[2
,3
]}

Gimzewski, James K. ^{[1
,2
,3
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA

[3] Natl Inst Mat Sci, Int Ctr Mat Nanoarchitecton Satellite MANA, Tsukuba, Ibaraki 3050047, Japan

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2010年 / 11卷 / 06期

关键词：

nano-characterization; dentistry; biofilms; bacterial adhesins; implants; dentine tubule; afm; interferometry; nanodentistry; ATOMIC-FORCE MICROSCOPY; LACTIC-ACID BACTERIA; STREPTOCOCCUS-MUTANS; RECOGNITION EVENTS; HUMAN SALIVA; CELL-WALL; EXOSOMES; ADHESION; PROTEIN; ELASTICITY;

D O I：

10.3390/ijms11062523

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

About 80% of US adults have some form of dental disease. There are a variety of new dental products available, ranging from implants to oral hygiene products that rely on nanoscale properties. Here, the application of AFM (Atomic Force Microscopy) and optical interferometry to a range of dentistry issues, including characterization of dental enamel, oral bacteria, biofilms and the role of surface proteins in biochemical and nanomechanical properties of bacterial adhesins, is reviewed. We also include studies of new products blocking dentine tubules to alleviate hypersensitivity; antimicrobial effects of mouthwash and characterizing nanoparticle coated dental implants. An outlook on future "nanodentistry" developments such as saliva exosomes based diagnostics, designing biocompatible, antimicrobial dental implants and personalized dental healthcare is presented.

引用

页码：2523 / 2545

页数：23

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