Instrumentation and calibration protocol for imaging dynamic features in dense-scattering media by optical tomography

被引:86
作者
Schmitz, CH
Graber, HL
Luo, HB
Arif, I
Hira, J
Pei, YL
Bluestone, A
Zhong, S
Andronica, R
Soller, I
Ramirez, N
Barbour, SLS
Barbour, RL
机构
[1] Suny Downstate Med Ctr, Dept Pathol, Brooklyn, NY 11203 USA
[2] Suny Downstate Med Ctr, Sci Med Instrumentat Ctr, Brooklyn, NY 11203 USA
[3] Polytech Univ, Metrotech Ctr 6, Dept Comp Sci, Brooklyn, NY 11201 USA
[4] Polytech Univ, Metrotech Ctr 6, Dept Elect Engn, Brooklyn, NY 11201 USA
[5] Midwood High Sch, Brooklyn, NY 11210 USA
[6] N Shore High Sch, Glen Head, NY 11545 USA
[7] NIRx Med Technol Corp, Glen Head, NY 11545 USA
关键词
D O I
10.1364/AO.39.006466
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Instrumentation is described that is suitable for acquiring multisource, multidetector, time-series optical data at high sampling rates (up to 150 Hz) from tissues having arbitrary geometries. The design rationale, calibration protocol, and measured performance features are given for both a currently used, CCD-camera-based instrument and a new silicon-photodiode-based system under construction. Also shown are representative images that we reconstructed from data acquired in laboratory studies using the described CCD-based instrument. (C) 2000 Optical Society of America OCIS codes: 110.3880, 170.3890, 170.1610, 170.5380, 170.3830.
引用
收藏
页码:6466 / 6486
页数:21
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