Initial interactions of subgenus D adenoviruses with a549 cellular receptors:: Sialic acid versus αv integrins

被引:114
作者
Arnberg, N [1 ]
Kidd, AH [1 ]
Edlund, K [1 ]
Olfat, F [1 ]
Wadell, G [1 ]
机构
[1] Umea Univ, Dept Virol, S-90185 Umea, Sweden
关键词
D O I
10.1128/JVI.74.16.7691-7693.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Selected members of the adenovirus family have been shown to interact with the coxsackie adenovirus receptor, or, integrins, and sialic acid on target cells. Initial interactions of subgenus D adenoviruses with target cells have until now been poorly characterized. Here, we demonstrate that adenovirus type 8 (Ad8), Ad19a, and Ad37 use sialic acid as a functional cellular receptor, whereas the Ad9 and Ad19 prototypes do not.
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收藏
页码:7691 / 7693
页数:3
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