BACKGROUND: For more than 40 years carotid endarterectomy (CE) has been used in the treatment of extracranial carotid disease for the prevention of stroke, Recent prospective clinical trials have confirmed the benefit of CE for both symptomatic and asymptomatic patients, Our purpose was to examine statewide trends in the numbers of CE over a 6-year time period and to evaluate outcomes, METHODS: Using data from the North Carolina Medical Database Commission (NCMDC) all CE procedures from 1988 to 1993 were identified, Numbers of CE were compared with the population and hospital admissions, Variables of length of stay, hospital charges, discharge disposition, and occurrence of stroke and death were analyzed. RESULTS: A total of 11,973 CE were performed in 6 years, Compared by admissions, population, and the proportion of elderly, the number of CE increased yearly, The stroke rate was 1.7% and the death rate 1.2% for an overall in-hospital stroke plus mortality rate of only 2.7%. CONCLUSIONS: From a diverse group of hospitals and a large number of surgeons and patients, this hospital-based study documents the acceptance and safety of CE in the treatment of extracranial carotid disease. (C) 1997 by Excerpta Medica, Inc.