A case of chronic myelomonocytic leukemia with isochromosome 14q

被引：9

作者：

Flaherty, L

Jarvis, A

Harris, M

Tyrrell, V

Smith, A

机构：

[1] Royal Alexandra Hosp Children, Dept Cytogenet, Westmead, NSW 2145, Australia

[2] Douglass Labs, N Ryde, NSW, Australia

来源：

CANCER GENETICS AND CYTOGENETICS | 1998年 / 101卷 / 02期

关键词：

D O I：

10.1016/S0165-4608(97)00254-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 7Z-year-old man with increased monocytes and eosinophils in the bone marrow was found to have an isochromosome, i(14q), as the safe abnormality on bone-marrow cytogenetics. Follow-up over 12 months with repeat cytogenetic testing of bone marrow specimens on three further occasions showed on additional abnormality consisting of an apparently balanced translocation, t(6;21)(p21.1;q22). This abnormality, together with other features, indicated disease progression. A review of seven reported cases of i(14q) revealed limited follow-up information. (C) Elsevier Science Inc., 1988.

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收藏

页码：134 / 137

页数：4

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