Activation of a plant plasma membrane Ca2+ channel by TGα1, a heterotrimeric G protein α-subunit homologue

被引：70

作者：

Aharon, GS ^{[1
]}

Gelli, A ^{[1
]}

Snedden, WA ^{[1
]}

Blumwald, E ^{[1
]}

机构：

[1] Univ Toronto, Dept Bot, Toronto, ON M5S 3B2, Canada

来源：

FEBS LETTERS | 1998年 / 424卷 / 1-2期

基金：

加拿大自然科学与工程研究理事会;

关键词：

heterotrimeric G protein; plasma membrane Ca2+ channel; TG alpha 1; signal transduction;

D O I：

10.1016/S0014-5793(98)00129-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Wild-type and GTPase-deficient recombinant TG alpha 1 were used along patch-clamp techniques to study the role of heterotrimeric G proteins in the regulation of the hyperpolarized active tomato plasma membrane Ca2+ channel. Recombinant alpha-subunits induced an increase in channel activity as shown by the increase in channel events and the mean open probability of the channel. Our results suggest a membrane-delimited pathway involving heterotrimeric G proteins in Ca2+ channel activation. (C) 1998 Federation of European Biochemical Societies.

引用

页码：17 / 21

页数：5

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