Smoking cessation is associated with reduced long-term mortality and the need for repeat interventions after coronary artery bypass grafting

被引:24
作者
Papathanasiou, Athanasios
Milionis, Haralampos
Toumpoulis, Ioannis
Kalantzi, Kallirroi
Katsouras, Christos
Pappas, Kostas
Michalis, Lampros
Goudevenos, John [1 ]
机构
[1] Univ Hosp Ioannina, Dept Cardiol, GR-45110 Ioannina, Greece
[2] Univ Hosp Ioannina, Dept Internal Med, GR-45110 Ioannina, Greece
来源
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION | 2007年 / 14卷 / 03期
关键词
coronary artery bypass grafting; mortality; smoking; surgery;
D O I
10.1097/HJR.0b013e3280403c68
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Design A prospective study. Methods We estimated the impact of smoking cessation on long-term mortality and the need for a revascularization procedure in 1027 patients undergoing a first-ever coronary artery bypass-grafting. Results and discussion Of the 640 active smokers, 44.7% continued smoking after CABG ('current smokers'), and 55.3% quit. During a 5310 patient-years follow-up, with never smokers as the reference group, current smokers (but not quitters) experienced a significant increase in total mortality (hazard ratio 2.6, 95% confidence interval 1.0-6.6) mainly owing to increased cardiovascular mortality (hazard ratio 4.8, 95% confidence interval 1.1-21.4), as well as increased need for a repeat revascularization procedure (hazard ratio 1.7, 95% confidence interval 1.0-2.9).
引用
收藏
页码:448 / 450
页数:3
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