Aquaporins in tumor growth and angiogenesis

被引：114

作者：

Nico, Beatrice ^{[1
]}

Ribatti, Domenico ^{[1
]}

机构：

[1] Univ Bari, Sch Med, Dept Human Anat & Histol, I-70124 Bari, Italy

来源：

CANCER LETTERS | 2010年 / 294卷 / 02期

关键词：

Angiogenesis; Aquaporins; Metastastis; Tumor growth; HUMAN BRAIN-TUMORS; EMBRYO CHORIOALLANTOIC MEMBRANE; WATER CHANNEL; COLORECTAL CARCINOGENESIS; GENE DISRUPTION; CELL-MIGRATION; EXPRESSION; EDEMA; CANCER; AQP5;

D O I：

10.1016/j.canlet.2010.02.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

The aquaporins (AQPs) are a family of transmembrane water channel proteins widely distributed and play a major role in transcellular and transepithelial water movement. Moreover, recent evidence indicates that AQPs may be involved in cell migration and angiogenesis. This review article summarizes literature data concerning the involvement of AQPs in tumor growth, angiogenesis and metastatic process and suggest a potential therapeutic approach by antagonizing their biological activity. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

引用

页码：135 / 138

页数：4

共 50 条

[1]

Aquaporins in brain: Distribution, physiology, and pathophysiology [J].

Badaut, T ;

Lasbennes, T ;

Magistretti, PJ ;

Regli, L .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2002, 22 (04) :367-378

[2]

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas [J].

Burghardt, B ;

Elkjær, ML ;

Kwon, TH ;

Rácz, GZ ;

Varga, G ;

Steward, MC ;

Nielsen, S .

GUT, 2003, 52 (07) :1008-1016

[3]

IN VIVO SILENCING OF AQUAPORIN-1 BY RNA INTERFERENCE INHIBITS ANGIOGENESIS IN THE CHICK EMBRYO CHORIOALLANTOIC MEMBRANE ASSAY [J].

Camerino, G. M. ;

Nicchia, G. P. ;

Dinardo, M. M. ;

Ribatti, D. ;

Svelto, M. ;

Frigeri, A. .

CELLULAR AND MOLECULAR BIOLOGY, 2006, 52 (07) :51-U30

[4]

Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer [J].

Chae, Young Kwang ;

Woo, Janghee ;

Kim, Mi-Jung ;

Kang, Sung Koo ;

Kim, Myoung Sook ;

Lee, Juna ;

Lee, Seung Koo ;

Gong, Gyungyub ;

Kim, Yong Hee ;

Soria, Jean Charles ;

Jang, Se Jin ;

Sidransky, David ;

Moon, Chulso .

PLOS ONE, 2008, 3 (05)

[5]

Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML) [J].

Chae, Young Kwang ;

Kang, Sung Koo ;

Kim, Myoung Sook ;

Woo, Janghee ;

Lee, Juna ;

Chang, Steven ;

Kim, Dong-Wook ;

Kim, Myungshin ;

Park, Seonyang ;

Kim, Inho ;

Keam, Bhumsuk ;

Rhee, Jiyoung ;

Koo, Nam Hee ;

Park, Gyeongsin ;

Kim, Soo-Hyun ;

Jang, Se-Eun ;

Kweon, Il-Young ;

Sidransky, David ;

Moon, Chulso .

PLOS ONE, 2008, 3 (07)

[6]

Increased expression of aquaporin 1 in human hemangioblastomas and its correlation with cyst formation [J].

Chen, Yizhao ;

Tachibana, Osamu ;

Oda, Masashi ;

Xu, Ruxiang ;

Hamada, Jun-ichiro ;

Yamashita, Junkoh ;

Hashimoto, Nobuo ;

Takahashi, Jun A. .

JOURNAL OF NEURO-ONCOLOGY, 2006, 80 (03) :219-225

[7]

Aquaporin-1 and endothelial nitric oxide synthase expression in capillary endothelia of human peritoneum [J].

Devuyst, O ;

Nielsen, S ;

Cosyns, JP ;

Smith, BL ;

Agre, P ;

Squifflet, JP ;

Pouthier, D ;

Goffin, E .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1998, 275 (01) :H234-H242

[8]

Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas [J].

Endo, M ;

Jain, RK ;

Witwer, B ;

Brown, D .

MICROVASCULAR RESEARCH, 1999, 58 (02) :89-98

[9]

Roles of aquaporin-3 in the epidermis [J].

Hara-Chikuma, Mariko ;

Verkman, A. S. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2008, 128 (09) :2145-2151

[10]

Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption [J].

Hara-Chikuma, Mariko ;

Verkman, A. S. .

MOLECULAR AND CELLULAR BIOLOGY, 2008, 28 (01) :326-332

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