A new antipsychotic effective neolignan from Firmiana simplex

被引：50

作者：

Son, YK

Lee, MH

Han, YN ^{[1
]}

机构：

[1] Seoul Natl Univ, Inst Nat Prod Res, Seoul 110460, South Korea

[2] Seoul Natl Univ, Coll Pharm, Seoul 110460, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2005年 / 28卷 / 01期

关键词：

Firmiana simplex; sterculiaceae; benzodioxane lignan; neolignan; antipsychotic effect;

D O I：

10.1007/BF02975132

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new neolignan, named simplidin was isolated from the the n-butanol extract of stem of Firmiana simplex, together with six known compounds, scopoletin (1), syrigaresinol (2), aquillochin (3), nitidanin (4), tamarixetin 3-rhamnoside (6), and quercitrin (7). On the basis of spectral and chemical evidence, simplidin (5) was determined to be rel-(7R,8R)-4,5,9,9'-tetrahydroxy-3,3'dimethoxy-7-O-5',8-O-4'-neolignan. All the six compounds were also isolated for the first time from this plant.

引用

页码：34 / 38

页数：5

共 14 条

[1]

BAE KH, 2000, MED PLANTS KOREA, P336

[2]

BERMES B, 1991, PHYTOCHEMISTRY, V30, P3087

[3] AQUILLOCHIN, A COUMARINOLIGNAN FROM AQUILARIA-AGALLOCHA [J].