The synthesis and transformation of ethyl 2-(2-acetyl-2-benzoyl-1-ethenyl)amino-3-dimethylaminopropenoate. A new synthesis of 2,3,4-trisubstituted pyrroles

被引：22

作者：

Malesic, M ^{[1
]}

Krbavcic, A

Golobic, A

Golic, L

Stanovnik, B

机构：

[1] Univ Ljubljana, Fac Pharm, Ljubljana 1000, Slovenia

[2] Univ Ljubljana, Fac Chem & Chem Technol, Ljubljana 1000, Slovenia

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 06期

关键词：

D O I：

10.1002/jhet.5570340619

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of ethyl 2-(2-acetyl-2-benzoyl-1-ethenyl)amino-3-dimethylaminopropenoate (4) from benzoylacetone (1) via 3-dimethylaminomethylenebenzoylacetone (2) and ethyl N-(2-acetyl-2-benzoy1-1-ethenyl)glycinate (3) and its transformation into 4-benzoyl-2-ethoxycarbonyl-3-methylpyrrole (9) is described. Cyclization of 4 into 9 represents a new synthesis of polysubstituted pyrroles.

引用

页码：1757 / 1762

页数：6

共 21 条

[1] TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS [J].