Raxibacumab

被引：71

作者：

Mazumdar, Sohini ^{[1
]}

机构：

[1] Tufts Univ, Sch Med, Grad Program Genet, Dept Anat & Cell Biol,Sackler Sch Grad Biomed Sci, Boston, MA 02111 USA

来源：

MABS | 2009年 / 1卷 / 06期

关键词：

raxibacumab; monoclonal antibody; anthrax; anti-PA; animal rule; bioterrorism; INHALATIONAL ANTHRAX; MONOCLONAL-ANTIBODY; PROTECTIVE ANTIGEN;

D O I：

10.4161/mabs.1.6.10195

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Raxibacumab (ABthrax) is a human IgGI monoclonal antibody against Bacillus anthracis protective antigen. HGS is currently providing stockpiles of the agent to the US government for use in the prevention and treatment of inhalation anthrax. As of May 2009, the candidate was undergoing review by the US Food and Drug Administration. The availability of bioterrorism countermeasures has become more important since the September 2001 anthrax attacks, and development of raxibacumab is a significant advance in this area.

引用

页码：531 / 538

页数：8

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