Is serum albumin a good marker for malnutrition in the physically impaired elderly?

被引:113
作者
Kuzuya, Masafumi [1 ]
Izawa, Sachiko [1 ]
Enoki, Hiromi [1 ]
Okada, Kiwako [1 ]
Iguchi, Akihisa [1 ]
机构
[1] Nagoya Univ, Grad Sch Med, Dept Geriatr, Showa Ku, Nagoya, Aichi 4668550, Japan
关键词
albumin; malnutrition; elderly; physical impairment; nutritional assessment; anthropometry; cholesterol; subjective global assessment;
D O I
10.1016/j.clnu.2006.07.009
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background and Aims: Although serum albumin is well known as a marker of nutritional. status, it has remained unclear whether impaired physical function affects serum albumin concentrations in older people. We examined whether hypoalbuminemia can be used as a marker of malnutrition in elderly subjects with various levels of physical impairment. Methods: A total of 262 elderly subjects without acute illness were enrolled from various geriatric settings. For the nutritional assessment, serum albumin, total, cholesterol, anthropometric measurements, and subjective global assessment (SGA) were determined. Physical function was evaluated by rating score of activity of daily Living (ADL). Results: As a whole, participants' serum albumin levels correlated with various nutritional parameters including anthropometric measurements and levels of serum total cholesterol as well as the SGA evaluation. However, after adjusting for age and gender, serum albumin Levels in participants with a low ADL function did not correlate with nutritional parameters. Approximately 80% participants with low ADL function who were evaluated as being well nourished according to SGA evaluation had serum albumin Levels Lower than 35 g/l. Conclusions: The utility of serum albumin and the traditional cutoff (35 g/l) in older people with low ADL function is questionable even among those without inflammation. (c) 2006 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
引用
收藏
页码:84 / 90
页数:7
相关论文
共 29 条
  • [1] Serum albumin is associated with skeletal muscle in elderly men and women
    Baumgartner, RN
    Koehler, KM
    Romero, L
    Garry, PJ
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1996, 64 (04) : 552 - 558
  • [2] A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION
    CHARLSON, ME
    POMPEI, P
    ALES, KL
    MACKENZIE, CR
    [J]. JOURNAL OF CHRONIC DISEASES, 1987, 40 (05): : 373 - 383
  • [3] Serum albumin concentration and clinical assessments of nutritional status in hospitalized older people: Different sides of different coins?
    Covinsky, KE
    Covinsky, MH
    Palmer, RM
    Sehgal, AR
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (04) : 631 - 637
  • [4] EVALUATING THE ACCURACY OF NUTRITIONAL ASSESSMENT TECHNIQUES APPLIED TO HOSPITALIZED-PATIENTS - METHODOLOGY AND COMPARISONS
    DETSKY, AS
    BAKER, JP
    MENDELSON, RA
    WOLMAN, SL
    WESSON, DE
    JEEJEEBHOY, KN
    [J]. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1984, 8 (02) : 153 - 159
  • [5] ROLE OF ALBUMIN IN HUMAN PHYSIOLOGY AND PATHOPHYSIOLOGY
    DOWEIKO, JP
    NOMPLEGGI, DJ
    [J]. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1991, 15 (02) : 207 - 211
  • [6] Prevalence of malnutrition on admission to four hospitals in England
    Edington, J
    Boorman, J
    Durrant, ER
    Perkins, A
    Giffin, CV
    James, R
    Thomson, JM
    Oldroyd, JC
    Smith, JC
    Torrance, AD
    Blackshaw, V
    Green, S
    Hill, CJ
    Berry, C
    McKenzie, C
    Vicca, N
    Ward, JE
    Coles, SJ
    [J]. CLINICAL NUTRITION, 2000, 19 (03) : 191 - 195
  • [7] EFFECTS OF POSTURE ON CONCENTRATIONS OF BLOOD-CONSTITUENTS IN HEALTHY-ADULTS - PRACTICAL APPLICATION OF BLOOD SPECIMEN COLLECTION PROCEDURES RECOMMENDED BY THE SCANDINAVIAN-COMMITTEE-ON-REFERENCE-VALUES
    FELDING, P
    TRYDING, N
    PETERSEN, PH
    HORDER, M
    [J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1980, 40 (07) : 615 - 621
  • [8] Hepatic proteins and nutrition assessment
    Fuhrman, P
    Charney, P
    Mueller, CM
    [J]. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 2004, 104 (08) : 1258 - 1264
  • [9] JAMES WPT, 1994, EUR J CLIN NUTR, V48, pS179
  • [10] Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    Janssen, I
    Heymsfield, SB
    Ross, R
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (05) : 889 - 896