Duration of growth suppressive effects of regular inhaled corticosteroids

被引:43
作者
Doull, IJM
Campbell, MJ
Holgate, ST
机构
[1] Univ Wales Hosp, Dept Child Hlth, Cyst Fibrosis Unit, Cardiff CF4 4XW, S Glam, Wales
[2] No Gen Hosp, Div Gen Practice, Sheffield S5 7AU, S Yorkshire, England
[3] Southampton Gen Hosp, Southampton SO9 4XY, Hants, England
关键词
asthma; corticosteroids; growth suppression;
D O I
10.1136/adc.78.2.172
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The growth of 50 children receiving regular inhaled corticosteroids was segregated into divisions of six weeks from the start of treatment and compared with their growth when not receiving regular corticosteroids using a random effects regression model. Growth suppression was most marked during the initial six weeks after starting treatment, with most suppression occurring during the initial 18 weeks. Thereafter the children's growth was similar to their growth when not receiving treatment. These findings have important consequences for patterns of treatment of asthma in children.
引用
收藏
页码:172 / 173
页数:2
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