Dyskeratosis congenita associated with three malignancies

被引：25

作者：

Baykal, C ^{[1
]}

Kavak, A

Gülcan, P

Büyükbabani, N

机构：

[1] Univ Istanbul, Ist Med Sch, Dept Dermatol, TR-34390 Istanbul, Turkey

[2] Abant Izzet Baysal Univ, Duzce Med Sch, Dept Dermatol, Duzce, Turkey

[3] SSK Okmeydani Hosp, Dept Dermatol, Istanbul, Turkey

[4] Univ Istanbul, Sch Med, Dept Pathol, Istanbul, Turkey

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2003年 / 17卷 / 02期

关键词：

dyskeratosis congenita; malignancy; Hodgkin's disease; squamous cell carcinoma; gastric adenocarcinoma;

D O I：

10.1046/j.1468-3083.2003.00585.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Dyskeratosis congenita is a rare inheritable disorder characterized by abnormalities of the skin, nails and oral mucosa. Aplastic anaemia resulting from bone marrow hypoplasia is a frequent cause of death. Squamous cell carcinoma developing from leukoplakia and visceral malignancies are other complications of the disease. We report here a case of dyskeratosis congenita in a man who developed three neoplasias of different systems over a period of many years. Squamous cell carcinoma and gastric adenocarcinoma manifested 17 years after the man was diagnosed with Hodgkin's disease.

引用

页码：216 / 218

页数：3

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