The Vertebrate Genome Annotation (Vega) database

被引:110
作者
Ashurst, JL [1 ]
Chen, CK [1 ]
Gilbert, JGR [1 ]
Jekosch, K [1 ]
Keenan, S [1 ]
Meidl, P [1 ]
Searle, SM [1 ]
Stalker, J [1 ]
Storey, R [1 ]
Trevanion, S [1 ]
Wilming, L [1 ]
Hubbard, T [1 ]
机构
[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, Cambs, England
关键词
D O I
10.1093/nar/gki135
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) has been designed to be a community resource for browsing manual annotation of finished sequences from a variety of vertebrate genomes. Its core database is based on an Ensembl-style schema, extended to incorporate curation-specific metadata. In collaboration with the genome sequencing centres, Vega attempts to present consistent high-quality annotation of the published human chromosome sequences. In addition, it is also possible to view various finished regions from other vertebrates, including mouse and zebrafish. Vega displays only manually annotated gene structures built using transcriptional evidence, which can be examined in the browser. Attempts have been made to standardize the annotation procedure across each vertebrate genome, which should aid comparative analysis of orthologues across the different finished regions.
引用
收藏
页码:D459 / D465
页数:7
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